Autor: |
Jiang, Weiming, Kang, Laiyi, Lu, Hong-Zhou, Pan, Xiaozhang, Lin, Qingneng, Pan, Qichao, Xue, Yile, Weng, Xinhua, Tang, Yi-Wei |
Zdroj: |
Clinical and Vaccine Immunology (formerly CDLI); July 2004, Vol. 11 Issue: 4 p811-813, 3p |
Abstrakt: |
ABSTRACTThe aim of this study was to establish reference ranges for lymphocyte subsets in Chinese adults. Venous blood specimens were obtained from 614 healthy, human immunodeficiency virus (HIV)-seronegative adults in Shanghai. Flow cytometry was used to determine percentages and absolute numbers of CD4 and CD8 T lymphocytes. Mean values for CD4 and CD8 lymphocytes were 727 and 540 cells/µl, respectively, yielding a CD4/CD8 ratio of 1.49. While CD8 lymphocyte values varied with age and gender, no significant differences in CD4 lymphocyte values were observed. Shanghai adults had approximately 100 fewer CD4 lymphocytes/µl on average than Caucasians, suggesting that lower CD4 lymphocyte cutoffs for classifying and monitoring HIV infection may be needed in China. |
Databáze: |
Supplemental Index |
Externí odkaz: |
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