Excretory-secretory antigens of Trypanosoma cruzi are potentially useful for serodiagnosis of chronic Chagas' disease.

Autor: Nakazawa, M, Rosa, D S, Pereira, V R, Moura, M O, Furtado, V C, Souza, W V, Barros, M N, Abath, F G, Gomes, Y M
Zdroj: Clinical and Vaccine Immunology (formerly CDLI); September 2001, Vol. 8 Issue: 5 p1024-7, 4p
Abstrakt: The reactivities of sera from chronic chagasic patients against the trypomastigote excreted-secreted antigens (TESA) of Trypanosoma cruzi strains with different biodemes were analyzed by TESA-blot and TESA-enzyme-linked immunosorbent assay (ELISA). Although both tests presented high sensitivity and specificity, TESA-ELISA is more appropriate for screening a larger number of samples.
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