| Autor: |
Nicoletti, Ferdinando, Di Marco, Roberto, Sacerdote, Paola, Meroni, PierLuigi, Mangano, Katia, Edwards, Carl, Bartorelli, Alberto, Bendtzen, Klaus, Panerai, Alberto |
| Zdroj: |
Antimicrobial Agents and Chemotherapy; May 2001, Vol. 45 Issue: 5 p1591-1594, 4p |
| Abstrakt: |
ABSTRACTMultifunctional protein 14 (MFP-14) is a ubiquitous protein that inhibits the production of tumor necrosis factor alpha (TNF-α) and gamma interferon (IFN-γ), which are involved in the pathogenesis of sepsis. Here, lipopolysaccharide (LPS)-induced lethality in mice was markedly reduced by MFP-14. The treatment also lowered LPS-induced levels of TNF-α and IFN-γ in the blood. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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