| Autor: |
Fisher, Nicholas, Rich, Peter R |
| Zdroj: |
JMB Online (Journal of Molecular Biology); March 2000, Vol. 296 Issue: 4 p1153-1162, 10p |
| Abstrakt: |
Many of the membrane-bound protein complexes of respiratory and photosynthetic systems are reactive with quinones. To date, no clear structural relationship between sites that bind quinone has been defined, apart from that in the homologous family of “type II” photosynthetic reaction centres. We show here that a structural element containing a weak sequence motif is common to the QAand QBsites of bacterial reaction centres and the Qisite of the mitochondrial bc1complex. Analyses of sequence databases indicate that this element may also be present in the PsaA/B subunits of photosystem I, in the ND4 and ND5 subunits of complex I and, possibly, in the mitochondrial alternative quinol oxidase. This represents a first step in the structural classification of quinone binding sites. |
| Databáze: |
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