Beneficial Effect of Lysine and Amino Acids on Cataractogenesis in Experimental Diabetes through Possible Antiglycation of Lens Proteins

Autor: SULOCHANA, K.N., PUNITHAM, R., RAMAKRISHNAN, S.
Zdroj: Experimental Eye Research; November 1998, Vol. 67 Issue: 5 p597-601, 5p
Abstrakt: Rats were given a single injection of streptozotocin. They became diabetic with a blood sugar of around 300 mg dL−1. They were divided into three groups of six rats each. Group II was the diabetic control. Each one of group III diabetic rats received daily 2 ml of 2% solution of lysine supplement orally. Group IV received daily 2 ml of a 2% solution of a mixture of amino acids supplement for 120 days. In addition there were 6 rats as normal control (Group I). Periodically ophthalmic examination was done by slit lamp. Blood glucose, proteins, hemoglobin, free amino acids, glycosylated hemoglobin and glycated lens proteins were also analysed. Body weight was recorded.
Databáze: Supplemental Index