| Autor: |
L. J. Clive, Derrick, Zhang, Junhu |
| Zdroj: |
Chemical Communications; March 21, 1997, Vol. 1997 Issue: 6 p549-550, 2p |
| Abstrakt: |
Glyoxylic acid diphenylhydrazone (2, Y = NPh2) and the corresponding O-benzyloxime (2, Y = OBn) are easily esterified in high yield by β-bromo alcohols, and the resulting esters undergo radical cyclization to α-(2,2-diphenylhydrazino) or α-(benzyloxyamino) lactones on treatment with tributyltin hydride; the initial radical can be formed by homolysis of a carbon–selenium bond as well as a carbon–bromine bond and, when applied to appropriate alcohols, the esterification–radical closure sequence can also be used to make six- or seven-membered lactones. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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