Reactions of 1,3-dihydrobenzo[c]thiophene 2,2-dioxides with electrophilic agents

Autor: Tashbaev, G.
Zdroj: Russian Chemical Bulletin; February 2005, Vol. 54 Issue: 2 p437-440, 4p
Abstrakt: Abstract Nitration, sulfonation, and iodination of 1,3-dihydrobenzo[c]thiophene 2,2-dioxide and its derivatives with electron-releasing and electron-withdrawing substituents were studied. Electrophilic substitution in 1,3-dihydrobenzo[c]thiophene 2,2-dioxide occurs at position 5. The presence of electron-withdrawing substituents in this position hinders further substitution, while electron-releasing substituents in positions 5 and 6 direct an electrophile to position 4.
Databáze: Supplemental Index
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