Endomyocardial Biopsies: A New Approach for Studying the Electrical and Mechanical Properties of Human Ventricular Myocardium

Autor: Gauthier, Chantal, Laurent, Karine, Charpentier, Flavien, Drouin, Emmanuel, Chevallier, Jean-Christophe, Marec, Hervé Le
Zdroj: Journal of Molecular and Cellular Cardiology; October 1994, Vol. 26 Issue: 10 p1267-1271, 5p
Abstrakt: The novel endomyocardial biopsy approach described here could facilitate the study of some human pathologies for which specimens are currently unavailable. Electrical and mechanical characteristics such as rate responses, effect of extracellular calcium concentration changes and β-adrenergic tone were similar to those determined for other human ventricular tissues, indicating that endomyocardial biopsies are suitable for physiological studies. This new source of cardiac tissues should facilitate the investigation of cellular mechanisms involved in the development of previously inaccessible human diseases. Copyright 1994, 1999 Academic Press
Databáze: Supplemental Index