| Autor: |
Haaf, Andreas, Butler, Jonathan G. P., Kent, Helen M., Fearnley, Ian M., Roberts, Thomas M., Neuhaus, David, Stewart, Murray |
| Zdroj: |
JMB Online (Journal of Molecular Biology); July 12, 1996, Vol. 260 Issue: 2 p251-260, 10p |
| Abstrakt: |
The major sperm protein (MSP) ofAscaris suummediates amoeboid motility by forming an extensive intermeshed system of cytoskeletal filaments analogous to that formed by actin in many amoeboid cells. We have used a combination of biochemical and NMR methods to show that, in contrast to actin, MSP exists in solution as a symmetrical dimer. This result has important implications for the mechanism of both MSP filament assembly and the recognition of different MSP isoformsin vivo. |
| Databáze: |
Supplemental Index |
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