| Autor: |
Vives, Sergi, Loucas, Bradford, Vazquez, Mariel, Brenner, David J., Sachs, Rainer K., Hlatky, Lynn, Cornforth, Michael, Arsuaga, Javier |
| Zdroj: |
Bioinformatics; July 2005, Vol. 21 Issue: 14 p3181-3181, 1p |
| Abstrakt: |
Motivation: The position of chromosomes in the interphase nucleus is believed to be associated with a number of biological processes. Here, we present a web-based application that helps analyze the relative position of chromosomes during interphase in human cells, based on observed radiogenic chromosome aberrations. The inputs of the program are a table of yields of pairwise chromosome interchanges and a proposed chromosome geometric cluster. Each can either be uploaded or selected from provided datasets. The main outputs are P-values for the proposed chromosome clusters. SCHIP is designed to be used by a number of scientific communities interested in nuclear architecture, including cancer and cell biologists, radiation biologists and mathematical/computational biologists. Availability: http://cramer.stat.ub.es/schip Contact:jarsuaga@cc.ucsf.edu Supplementary information: http://cramer.stat.ub.es/schip/help.htm |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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