| Autor: |
Ueberbacher, Bernhard J., Osprian, Ingrid, Mayer, Sandra F., Faber, Kurt |
| Zdroj: |
European Journal of Organic Chemistry; April 2005, Vol. 2005 Issue: 7 p1266-1270, 5p |
| Abstrakt: |
A chemoenzymatic, asymmetric total synthesis of the anti-biotic (R)-fridamycin E has been accomplished following a biocatalytic deracemization procotol. The key step comprises the construction of the chiral side-chain from a functionalized rac-2,2-disubstituted oxirane via a kinetic resolution/stereoinversion sequence without formation of the undesiredstereoisomer. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005) |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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