| Autor: |
Rosilio, Véronique, Madelmont, Georgette, Akiyoshi, Kazunari, Sunamoto, Junzo, Baszkin, Adam |
| Zdroj: |
Journal of Colloid and Interface Science; February 1994, Vol. 162 Issue: 2 p418-424, 7p |
| Abstrakt: |
The thermal behavior of dimyristoylphosphatidylcholine (DMPC)-cholesteryl-pullulan (CHP45-0.6) systems containing increasing water contents (wt%) has been investigated by DSC. The thermograms of annealed samples reveal that the presence of CHP45-0.6 shifts the appearance of the main transition peak of the lipid, corresponding to the coexistence of its Pn', phase with Ln phase, toward lower water contents. Moreover, the pretransition peak which is related to the presence of free water in the case of pure DMPC was insensitive to the variation in the water content for its mixtures with CHP45-0.6. Also, the appearance of free water in the DMPC-CHP (1:1 w/w) mixture was observed at a water content higher by a factor 3 than that for the pure DMPC. All these results indicate that the increase in fluidity takes place with addition of CHP45-0.6 to the system. They also show that when the free water appears at higher hydration levels the fluidization of the system is enhanced. The stability of the studied systems results from the interaction of the lipid with CHP45-0.6 and from water content and varies as indicated by the total transition enthalpy and entropy changes in the order DMPC-CHP (1:1 w/w) > DMPC-CHP (5:1 w/w) > DMPC. Copyright 1994, 1999 Academic Press |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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