| Autor: |
Landeau, Jean-Marie, Pellat, Bernard, Hornebeck, William |
| Zdroj: |
Cell Biology International; February 1994, Vol. 18 Issue: 2 p111-118, 8p |
| Abstrakt: |
Elastin-derived peptides were previously shown to influence human skin fibroblasts (HSF) chemotaxis and proliferation (Ghuysen et al., 1992). We report here that culturing HSF on κ-elastin (κE) but not onto fibronectin (FN) enhanced the secretion of latent elastinolytic activity. The proteinase involved was identified as the 72 kDa gelatinase A. Moreover, HSF-κE as well as HSF-FN interactions modulated the secretions of Il1 induced expressions of elastinolytic activities. Copyright 1994, 1999 Academic Press |
| Databáze: |
Supplemental Index |
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