Meta-Analysis of Sentinel Lymph Node Biopsy in Breast Cancer

Autor: Miltenburg, Darlene M., Miller, Charles, Karamlou, Tara B., Brunicardi, F.Charles
Zdroj: Journal of Surgical Research; June 1999, Vol. 84 Issue: 2 p138-142, 5p
Abstrakt: Background.Sentinel lymph node biopsy (SLNB) is a minimally invasive way to diagnose axillary lymph node (ALN) metastases in breast cancer. The most important features are ability to identify the SLN (I.D. rate), how often the SLN and ALN pathology match (concordance), and how often the SLN is negative for cancer when the ALNs are positive (false negative). Technique and patient criteria for SLNB vary among studies. This study performed meta-analysis of published studies to determine the I.D., concordance, and false negative rate (1) overall and for (2) both blue dye and radiocolloid, (3) the injection method, (3) palpable and nonpalpable ALNs, and (4) invasive and in situdisease.
Databáze: Supplemental Index