Infectious Encephalitis: A persistent clinical challenge

Autor: Azhar Munir, Armghan Azhar, McCort, Margaret, Burack, Daniel A.
Zdroj: Medical Clinics of North America; 20240101, Issue: Preprints
Abstrakt: Encephalitis is a serious neurological condition that frequently results in long-term neurological complications. Effective management in adults with suspected infectious encephalitis involves testing the cerebrospinal fluid for common pathogens, including herpes simplex virus-1 (HSV-1), varicella-zoster virus (VZV), enteroviruses, and West Nile virus. Early initiation of high-dose intravenous acyclovir is recommended. Epidemiologic clues and immune status of the host should be considered when attempting to identify the cause of encephalitis.When no cause is identified, next-generation sequencing or a brain biopsy may be warranted. Further research should focus on developing new therapeutic options for this challenging clinical syndrome.
Databáze: Supplemental Index