The GATA-3 dependent transcriptome and tumor microenvironment are regulated by eIF4E and XPO1 in T-cell lymphomas

Autor: Kady, Nermin, Abdelrahman, Suhaib, Rauf, Ahmar M., Burgess, Alyssa, Weiss, Jonathan, Gunasekara, Hirushi, Ramseier, Neal, Maine, Ira P., Zevallos-Morales, Alejandro, Perez-Silos, Vanessa, Wolfe, Ashley, Hristov, Alexandra C., Brown, Noah A., Inamdar, Kedar, Sverdlov, Maria, Hu, Ying S., Murga-Zamalloa, Carlos, Wang, Chenguang, Wilcox, Ryan A.
Zdroj: Blood; 20240101, Issue: Preprints
Abstrakt: eIF4E/XPO1 collaboratively transport GATA-3 and GATA-3 targets and are thus therapeutic vulnerabilities in GATA-3-driven T-cell lymphomas.
Databáze: Supplemental Index