Efficacy and safety of venetoclax plus azacitidine for patients with treatment-naive high-risk myelodysplastic syndromes

Autor: Garcia, Jacqueline S., Platzbecker, Uwe, Odenike, Olatoyosi, Fleming, Shaun, Fong, Chun Yew, Borate, Uma, Jacoby, Meagan A., Nowak, Daniel, Baer, Maria R., Peterlin, Pierre, Chyla, Brenda, Wang, Huipei, Ku, Grace, Hoffman, David, Potluri, Jalaja, Garcia-Manero, Guillermo
Zdroj: Blood; 20250101, Issue: Preprints
Abstrakt: •Venetoclax (14 days) + azacitidine regimen was well tolerated in patients with treatment-naive HR MDS, with no unexpected safety findings.•The regimen produced CR in 29.9% of patients, marrow CR in 50.5%, and 26-month median OS.
Databáze: Supplemental Index