| Autor: |
Houston, Michael, Seo, Gang, Fang, Feng, Park, Jeong-Ho, Park, Hyung-Soon, Roh, Jinsook, Zhang, Yingchun |
| Zdroj: |
IEEE Journal of Biomedical and Health Informatics; December 2024, Vol. 28 Issue: 12 p7164-7174, 11p |
| Abstrakt: |
Objective: The changes in neural drive to muscles associated with modulation of inter-muscular coordination in the upper extremity have not yet been investigated. Such information could help elucidate the neural mechanisms behind motor skill learning. Methods: Six young, neurologically healthy participants underwent a six-week training protocol to decouple two synergist elbow flexor muscles as a newly learned motor skill in the isometric force generation in upward and medial directions. Concurrent electroencephalography and surface electromyography from twelve upper extremity muscles were recorded in two conditions (As-Trained & Habitual) across two assessments (Week 0 vs. Week 6). Changes to inter-muscular connectivity (IMC), functional muscle networks, cortico-muscular connectivity (CMC), cortico-cortical connectivity (CCC) as well as functional brain network controllability (FBNC) associated with the modulation of inter-muscular coordination patterns were assessed to provide a perspective on the neural mechanisms for the newly learned motor skills. Results: Significant decreases in elbow flexor IMC, CMC, and increases in CCC were observed. No significant changes were observed for FBNC. Conclusion: The results of this study suggest that modulating the inter-muscular coordination of the elbow flexor muscle synergy during isometric force generation is associated with multiple yet distinct changes in functional connectivity across the central and peripheral perspectives. Significance: Understanding the neural mechanisms of modulating inter-muscular coordination patterns can help inform motor rehabilitation regimens. |
| Databáze: |
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