| Autor: |
Nascimento de Campos, Hevila Gabrieli, Gennari, Solange Maria, da Silva, Ryan Emiliano, Soares, Herbert Sousa, Costa, Jaciara de Oliveira Jorge, de Azevedo, Sergio Santos, Marcili, Arlei |
| Zdroj: |
Journal of Medical Entomology; November 2024, Vol. 61 Issue: 6 p1519-1523, 5p |
| Abstrakt: |
Leishmaniasis are zoonosis widely spread in Brazil, caused by the protozoan of the genus Leishmania, which includes several species. The disease manifests itself in the visceral or tegumentary form, and the main reservoir is the dogs. Manaus is the largest city in the Brazilian Amazon region, and despite the importance of the municipality, practically nothing is known about leishmaniosis in humans and animals. The objective of this study was to evaluate the occurrence and risk factors associated with the presence of Leishmania infantumin domiciliated dogs from Manaus. Molecular (polymerase chain reaction) and serological (immunofluorescent antibody test) methods were used as an indication of the circulation of the parasite. Blood samples for 154 domiciled dogs were obtained, and prevalence ratio and analysis of the variables were performed. Serum antibodies anti-Leishmaniaspp. were detected in 20.8% (95% CI: 14.4%–27.2%). Access to the street and zone of residence (P< 0.01) were associated with higher seropositivity. Molecular diagnosis for L. infantumdetected positivity in 60 (39%) of the 154 (95% CI: 31.3%–46.7%) animals, and the variables street access, contact with dogs, and zone of residence were associated with higher frequencies of positivity (P< 0.05). Both serology and molecular diagnosis detected positive dogs in the municipality. This is the first description of the circulation of L. infantuminfecting dogs in Manaus. As the municipality is classified as nonendemic, studies of isolation and characterization of the isolate must be done urgently. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
