The Efficacy of Thyroidectomy for Graves' Disease: A Meta-analysis

Autor: Palit, Tapash K., Miller, Charles C., Miltenburg, Darlene M.
Zdroj: Journal of Surgical Research; May 2000, Vol. 90 Issue: 2 p161-165, 5p
Abstrakt: Background.Surgery for Graves' disease was largely replaced in the mid-1900s by radioiodine and antithyroid drugs, due to the belief that they were more safe and effective. Since then, thyroid surgery has improved with preoperative drug therapy and modern operative techniques. Recent clinical studies of thyroidectomy for Graves' disease may not reflect outcomes accurately because of small sample size, especially when estimating ideal thyroid remnant size. The purpose of this study was to combine modern clinical trials and use meta-analysis to determine the overall efficacy of both total (TT) and subtotal thyroidectomy (ST) for Graves' disease, compare thyroid function and complications rates of TT and ST, and determine ideal thyroid remnant size.
Databáze: Supplemental Index