Effect of Coprinus atramentariuson the metabolism of ethanol in mice

Autor: Coldwell, B B, Genest, K, Hughes, D W
Zdroj: Journal of Pharmacy and Pharmacology; March 1969, Vol. 21 Issue: 3 p176-179, 4p
Abstrakt: The ethanol-soluble material extracted from Coprinus atramentariuswas more toxic to mice, as measured by the LD50 and potentiation of the ethanol-induced sleeping time, than the whole mushroom or the residue remaining after ethanol extraction. Also, the ethanol-soluble fraction when fed to mice 4 h before administration of ethanol markedly increased the blood acetaldehyde and ethanol levels.
Databáze: Supplemental Index