Autor: |
Khalil, Saleh A H, Nasipuri, R N |
Zdroj: |
Journal of Pharmacy and Pharmacology; February 1973, Vol. 25 Issue: 2 p138-142, 5p |
Abstrakt: |
The uptake of benzoic acid on sulphadimidine particles has been investigated. Depending on the concentration of sulphadimidine in the system, benzoic acid was adsorbed to the extent of 94%. Data from the adsorption experiments were shown to fit a Langmuir plot for systems containing up to 0.2 g 100 ml−1sulphadimidine. The suppressive effect of three hydrophilic polymers on adsorption was studied; the results followed the sequence: Polyvinylpyrrolidone (PVP) > methylcellulose > sodium carboxymethylcellulose. Dialysis experiments revealed that, within the range of concentrations used, neither PVP nor methylcellulose was significantly bound to benzoic acid. |
Databáze: |
Supplemental Index |
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