| Autor: |
Kumar, Vivek, Bisoyi, Akash, Beevi V, Fathima, Yatham, Veera Reddy |
| Zdroj: |
The Journal of Organic Chemistry; November 2024, Vol. 89 Issue: 22 p16964-16968, 5p |
| Abstrakt: |
Herein, we report a metal-free light-induced three-component reaction for the synthesis of polychloroalkyl-substituted quinoxalin-2(1H)-ones using commercially available alkenes, polyhalo alkanes, and quinoxalin-2(1H)-ones. Preliminary mechanistic studies suggested the generation of radical intermediates via an EDA-complex, single electron transfer, or halogen atom transfer pathway. Under mild reaction conditions, various alkenes and quinoxalin-2(1H)-ones containing different functional groups are compatible, providing the corresponding polychloroalkyl-substituted quinoxalin-2(1H)-ones in moderate to good yields. |
| Databáze: |
Supplemental Index |
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