Contraction induced by (-)-tartaric acid on rat isolated gastric fundus and its inhibition with indomethacin

Autor: Tug̀rul, Levent, Özer, Asli
Zdroj: Journal of Pharmacy and Pharmacology; August 1985, Vol. 37 Issue: 8 p583-584, 2p
Abstrakt: Tartaric acid-evoked contractions of the rat isolated fundus could not be antagonized by atropine sulphate or methysergide hydrogen maleate, but were partially reduced by mepyramine hydrochloride. The contractions were prevented by indomethacin (25 μ ml−1) although the tissue remained sensitive to PGE2.
Databáze: Supplemental Index