| Autor: |
Rosenfield, Kenneth, Bowers, Terry R., Barnett, Christopher F., Davis, George A., Giri, Jay, Horowitz, James M., Huisman, Menno V., Hunt, Beverley J., Keeling, Brent, Kline, Jeffrey A., Klok, Frederikus A., Konstantinides, Stavros V., Lanno, Michelle T., Lookstein, Robert, Moriarty, John M., Ní Áinle, Fionnuala, Reed, Jamie L., Rosovsky, Rachel P., Royce, Sara M., Secemsky, Eric A., Sharp, Andrew S. P., Sista, Akhilesh K., Smith, Roy E., Wells, Phil, Yang, Joanna, Whatley, Eleni M., Abudi, Tami, Adams, George, Ahmad, Hajira, Ajao, Adebola, Archard, Erin, Auger, William, Avila-Tang, Erika, Barnes, Geoff, Barnett, Christopher, Bashir, Riyaz, Benenati, James, Berman, Aaron, Bowers, Terry, Buck, Michael, Burnett, Allison, Cameron, Scott, Cavanaugh, Kenneth, Cerminaro, Michael, Daniel, Daniel, Daves, Seanna, Davis, George, Dicks, Andrew, Elder, Mahir, Farrell, Ann, Garman, Alissa, Gatzemeier, Jamee, Giannikopoulos, Demetri, Gibson, Michael, Goldberg, Joshua, Gonsalves, Carin, Grodzin, Charles, Gundert, Emily, Gurley, John, Heresi, Gustavo, Hlozek, Kristen, Hoerst, Stephen, Hooks, Brandon, Horowitz, James, Jaber, Wissam, Jaff, Michael, Jimenez, David, Johnston-Cox, Hillary, Kaatz, Scott, Kolluri, Raghu, Laird, John, Lake, Leslie, Langston, Matthew, Lossef, Steven, Love, Charles, Mackel, Julie, Massaro, Lori, McDaniel, Michael, McNally, Vicki, Merli, Geno, Mina, Bushra, Monreal, Manuel, Moores, Lisa, Morris, Timothy, Nossair, Fadi, O’Connell, Gregory, O’Corragain, Oisin, Ouriel, Kenneth, Parikh, Sahil, Piazza, Gregory, Pohlson, Katie, Polverini, Peter, Pomeroy, Jordan, Pugliese, Steve, Pullin, Brian, Quinto, Brian, Rali, Parth, Rivera-Lebron, Belinda, Robertson, Bill, Rosengard, Bruce, Shaw, Miranda, Simonton, Chuck, Sista, Akhilesh, Smith, Roy, Spyropoulos, Alex, Srivastava, Sanjay, Sterling, Keith, Strauss, Jayme, Taber, Margaret, Tapson, Victor, Tawney, Adam, Tu, Thomas, Valent, Tom, Venkat, Venkat, Walach, Elad, Ward, Rebecca, Ward, Adam, Weinberg, Ido, Wells, Phil, West, Frances Mae, West, Nick, Whatley, Eleni, Yang, Joanna, Yongpravat, Charlie |
| Zdroj: |
Circulation (Ovid); 20240101, Issue: Preprints |
| Abstrakt: |
Recent advances in therapy and the promulgation of multidisciplinary pulmonary embolism teams show great promise to improve management and outcomes of acute pulmonary embolism (PE). However, the absence of randomized evidence and lack of consensus leads to tremendous variations in treatment and compromises the wide implementation of new innovations. Moreover, the changing landscape of health care, where quality, cost, and accountability are increasingly relevant, dictates that a broad spectrum of outcomes of care must be routinely monitored to fully capture the impact of modern PE treatment. We set out to standardize data collection in patients with PE undergoing evaluation and treatment, and thus establish the foundation for an expanding evidence base that will address gaps in evidence and inform future care for acute PE. To do so, >100 international PE thought leaders convened in Washington, DC, in April 2022 to form the Pulmonary Embolism Research Collaborative. Participants included physician experts, key members of the US Food and Drug Administration, patient representatives, and industry leaders. Recognizing the multidisciplinary nature of PE care, the Pulmonary Embolism Research Collaborative was created with representative experts from stakeholder medical subspecialties, including cardiology, pulmonology, vascular medicine, critical care, hematology, cardiac surgery, emergency medicine, hospital medicine, and pharmacology. A list of critical evidence gaps was composed with a matching comprehensive set of standardized data elements; these data points will provide a foundation for productive research, knowledge enhancement, and advancement of clinical care within the field of acute PE, and contribute to answering urgent unmet needs in PE management. Evidence produced through the Pulmonary Embolism Research Collaborative, as it is applied to data collection, promises to provide crucial knowledge that will ultimately produce a robust evidence base that will lead to standardization and harmonization of PE management and improved outcomes. |
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