Dermatological toxicity associated with the use of gilteritinib in relapsed acute myeloid leukemia with FLT3 mutation: a case report

Autor: Martín Roldán, Alicia, Alarcón-Payer, Carolina, Sánchez Suárez, María Del Mar, Jiménez Morales, Alberto
Zdroj: Anti-Cancer Drugs; October 2024, Vol. 35 Issue: 9 p872-874, 3p
Abstrakt: We present a case of a patient diagnosed with FLT3 mut+ acute myeloid leukemia with FLT3 and NMP1 mutations who did not respond to standard induction and consolidation treatment with chemotherapy. Due to the FLT3mut+ gene mutation and intermediate cytogenetic risk, treatment with gilteritinib is requested. After treatment she experienced a neutrophilic dermatosis and granuloma annulare that was resolved with gilteritinib dose reduction and specific treatment in coordination with the dermatology department.
Databáze: Supplemental Index