| Autor: |
Cizikovs, Aleksandrs, Zagorska, Paula A., Grigorjeva, Liene |
| Zdroj: |
Organic Letters; November 2024, Vol. 26 Issue: 44 p9536-9540, 5p |
| Abstrakt: |
Herein, we report a simple method for the synthesis of 3-benzazepine derivatives via a cobalt-catalyzed, picolinamide-directed α-amidoacrylate C(sp2)–H bond functionalization approach. The reactions utilize calcium carbide as an inexpensive, easy-to-handle, and solid acetylene source, and simple CoCl2as the reaction catalyst. Excellent functional group tolerance is observed, yielding diverse substituted 3-benzazepine derivatives in good to excellent yields. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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