| Abstrakt: |
Background: Ovarian malignancies in young females have a pivotal incidence in gynecological oncology. Aims & Objectives: To determine the frequency, clinical presentation, tumor characteristics, management, and reproductive outcomes of children and adolescents with ovarian neoplasm below 20 years of age in our Odisha population. Material & methods: This is a retrospective observational study done in the Department of Gynecologic Oncology, AHPGIC, Cuttack, Odisha. Girls below 20 years with ovarian tumors who had undergone staging laparotomy/cytoreductive surgery at AHPGIC between November 2012 to October 2022 were included. Results: Girls below the age of 20 with malignant ovarian tumors who had undergone staging or debulking surgery have been included. The mean age in our study was 15.5 years [7–19 years]. Among the 47 malignant cases, only three cases were in the age group below ten years (6.38%). Abdominal distension (52.3%), abdominal pain were the most common complaints in these patients. Most common was stage 1, followed by stage III (13/47 cases) and stage II (11/47 cases). Only four patients had stage IV disease. Of the 47 cases included in our study, 43 cases of staging laparotomy (91.48%) and four cases (8.51%) of interval debulking surgery had been performed. 44/47 cases (93.61%) of fertility preserving surgery have been done. 6.38% (3/47 cases) of TAH BSO with debulking had been done. 11 patients of 47 patients (23.40%) did not receive any chemotherapy. The remaining 36 patients (76.60%) had received chemotherapy. Median follow-up time was 47 months (14–122 mo.). Out of total 47 patients included, seven patients (14.89%) have recurred, and four patients (8.51%) have died till date. 40 patients have been analyzed for their reproductive outcomes. Six term deliveries and two preterm deliveries have been documented till date. Conclusion: A pediatric malignant ovarian tumor is a highly treatable condition if it is in an early stage when first diagnosed. Among the malignant ovarian tumors, ovarian germ cell cancers are the commonest, and thus a strong index of suspicion should be advocated in primary care givers who encounter adnexal masses in this age group. |
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