| Autor: |
Ding, Ran, Gang, Dong, Tang, Xu, Wu, Tao, Liu, Lei, Mao, Yue-Yuan, Li, Zi-Rong, Gao, Hui |
| Zdroj: |
The Journal of Organic Chemistry; November 2024, Vol. 89 Issue: 21 p15733-15738, 6p |
| Abstrakt: |
Remarkable progress has been made in the radical cascade cyclization of heteroaryl- or aryl-tethered alkenes to construct benzene-fused frameworks via the cracking of aryl C–H bonds. In contrast, the radical cascade cyclization of linear dienes through the cracking of vinyl C–H bonds to construct nonbenzene-fused ring frameworks with endocyclic double bonds has significantly lagged behind, and major advances have largely been restricted to the generation of 5-membered heterocycles, such as pyrrolinones. Herein, we report the silver-mediated regioselective sulfonylation-cyclization of linear dienes with sodium sulfinates to form sulfonylated 6- and 7-membered cyclic enamines. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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