Robust Model Predictive Control of a Vaccine Production Unit

Autor: Benavides, Micaela, Dewasme, Laurent, Gerkens, Pascal, de Lannoy, Gaël, Wouwer, Alain Vande
Zdroj: IFAC-PapersOnLine; January 2024, Vol. 58 Issue: 23 p121-126, 6p
Abstrakt: In this paper, nonlinear model predictive controllers (NMPC) are proposed to optimize the biomass productivity of yeast fed-batch cultures. Their predictions are driven by a mechanistic model developed using a few industrial vaccine production data sets. The limited amount of data causes high parametric uncertainty levels and, to address this issue, a robust tube-based MPC is proposed and its robustness is assessed by a Monte-Carlo analysis, and compared to the classical MPC formulation.
Databáze: Supplemental Index