Genetic risk score for coronary artery calcification and its predictive ability for coronary artery disease

Autor: Mishra, Pashupati P., Mishra, Binisha H., Lyytikäinen, Leo-Pekka, Goebeler, Sirkka, Martiskainen, Mika, Hakamaa, Emma, Kleber, Marcus E., Delgado, Graciela E., März, Winfried, Kähönen, Mika, Karhunen, Pekka J., Lehtimäki, Terho
Zdroj: American Journal of Preventive Cardiology; December 2024, Vol. 20 Issue: 1
Abstrakt: The modest added predictive value of the existing genetic risk scores (GRSs) for coronary artery disease (CAD) could be partly due to missing genetic components, hidden in the genetic architecture of intermediate phenotypes such as coronary artery calcification (CAC). In this study, we investigated the predictive ability of CAC GRS for CAD.
Databáze: Supplemental Index