Chronic lymphocytic leukemia treated successfully by syngeneic marrow transplantation

Autor: Spitzer, T. R., Cottler‐Fox, M., Jacobson, R. J., Torrisi, J., Cahill, R., Deeg, H. J.
Zdroj: Clinical Transplantation; October 1989, Vol. 3 Issue: 5 p286-289, 4p
Abstrakt: Marrow transplantation is a potentially curative treatment for patients with lymphohematopoietic malignancies. We report here a case of syngeneic transplantation in a 39‐year‐old male with chemotherapy‐resistant progressive chronic lymphocytic leukemia. Following conditioning therapy with fractionated total body irradiation, etoposide and cyclophosphamide and transplantation from a monozygotic twin brother, the patient achieved a complete remission and remains disease‐free 15 months after transplant. This observation indicates that, in principle, chronic lymphocytic leukemia is a disease curable by marrow transplantation.
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