Non-saponin from Panax ginsengmaintains blood-brain barrier integrity by inhibiting NF-κB and p38 MAP kinase signaling pathways to prevent the progression of experimental autoimmune encephalomyelitis

Autor: Oh, Jinhee, Ha, Yujeong, Kwon, Tae Woo, Jo, Hyo-Sung, Moon, Sang-Kwan, Lee, Yoonsung, Nah, Seung-Yeol, Kim, Min Soo, Cho, Ik-Hyun
Zdroj: Journal of Ginseng Research; 20240101, Issue: Preprints
Abstrakt: The non-saponin (NS) fraction is an important active component of Panax ginseng,with multifunctional pharmacological activities including neuroprotective, immune regulatory, anti-inflammatory, and antioxidant effects. However, the effects of NSs on multiple sclerosis (MS), a chronic and autoimmune demyelinating disorder, have not yet been demonstrated.
Databáze: Supplemental Index