Exercise Training and Rehabilitation in Cardiac Amyloidosis (ERICA) Study

Autor: Marra, Alberto M., Palmiero, Giuseppe, Losi, Mariangela, Mallardo, Mario, Galati, Alfonso, Bossone, Eduardo, Esposito, Giovanni, Calabrò, Paolo, Cittadini, Antonio, Limongelli, Giuseppe, Crisci, Giulia, Monda, Emanuele, Esposito, Giorgia, Verrillo, Federica, De Mare, Andrea, Dongiglio, Francesca, Ventura, Dino Della, Misserafiti, Bruna, Caruso, Roberto, Gabriele, Michele, Palermo, Pietro
Zdroj: Heart Failure Clinics (Science Direct); 20240101, Issue: Preprints
Abstrakt: Notwithstanding the dramatic improvement associated with Tafamidis in Heart Failure due to wild-type transthyretin cardiac amyloidosis (ATTRwt-CA), the effect of exercise training on ATTRwt-CA remains unexplored. We hereby present rationale and design of the Exercise training and Rehabilitation in Cardiac Amyloidosis study. This interventional, controlled study will randomize ATTRwt-CA patients into a control group and a training group. Primary endpoint will be the distance obtained at the 6-min walk test. Quality-of-life, peak oxygen consumption, left and right heart architecture and function, and natriuretic peptides will be secondary endpoints.
Databáze: Supplemental Index