| Autor: |
Núñez-Tapia, Israel Alfonso, Vázquez-Vázquez, Febe Carolina, Mendoza, Olga Flores, Bucio-Galindo, Lauro, Álvarez-Pérez, Marco Antonio, Barba, María Cristina Piña |
| Zdroj: |
Biomedical Materials & Devices; 20240101, Issue: Preprints p1-11, 11p |
| Abstrakt: |
This study investigates the extraction and characterisation of collagen derived from fish skin and scales, the collagens obtained were used to produce membranes which were subsequently cross-linked by EDC/NHS. A comprehensive investigation of their microstructure, composition, mechanical properties, swelling, degradation, thermal properties and a 24 h cell viability test was carried out. The results showed that the yields of collagen from skin and fish scales were 25.14 ± 2.90 and 29.26 ± 2.53%, respectively. Mechanical stress tests showed that membranes made from fish skin collagen and commercial collagen had comparable load-bearing capacities before failure. The Young’s modulus of the membranes was 9.45 MPa ± 1.77 for commercial collagen, 5.76 MPa ± 0.74 for fish skin collagen and 2.43 MPa ± 0.78 for fish scale collagen, this similarity was maintained in degradation tests and at denaturation temperature (75 °C).These results demonstrate the viability of collagen derived from marine by-products as an effective and efficient alternative for biomedical and tissue engineering applications. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
Full text from SpringerLink