Synthetic lincosamides iboxamycin and cresomycin are active against ocular multidrug-resistant methicillin-resistant Staphylococcus aureuscarrying ermgenes

Autor: André, Camille, Wu, Kelvin J.Y., Myers, Andrew G., Bispo, Paulo J.M.
Zdroj: Journal of Global Antimicrobial Resistance; December 2024, Vol. 39 Issue: 1 p144-148, 5p
Abstrakt: •New synthetic lincosamides, iboxamycin and cresomycin, display potent in vitroactivity against ocular methicillin-resistant Staphylococcus aureus(MRSA) isolates.•Both drugs are active against widespread MRSA clonal complexes CC8 and CC5.•The in vitropotencies of iboxamycin and cresomycin are not impacted by multidrug-resistance phenotypes or by the presence of ermgenes when compared with clindamycin.
Databáze: Supplemental Index