Aspergillus fumigatusextract modulates human eosinophils via NOD2 and oxidative stress

Autor: Sasaki, Hisashi, Miyata, Jun, Kawashima, Yusuke, Konno, Ryo, Ishikawa, Masaki, Hasegawa, Yoshinori, Onozato, Ryuta, Otsu, Yo, Matsuyama, Emiko, Sunata, Keeya, Masaki, Katsunori, Kabata, Hiroki, Kimizuka, Yoshifumi, Abe, Tomoe, Ueki, Shigeharu, Asano, Koichiro, Kawana, Akihiko, Fukunaga, Koichi
Zdroj: Allergology International; January 2025, Vol. 74 Issue: 1 p156-165, 10p
Abstrakt: Aspergillus fumigatusis a pathogenic fungus known to be associated with severe asthma and allergic bronchopulmonary mycosis. However, the precise mechanisms underlying airway inflammation remain unclear. In this study, we investigated the direct modulation of human eosinophils by A. fumigatusand identified the specific mechanism of airway inflammation.
Databáze: Supplemental Index