Pirfenidone and candesartan ameliorate morphological damage in mild chronic anti-GBM nephritis in rats.

Autor: Leh, Sabine, Vaagnes, Øyvind, Margolin, Solomon B, Iversen, Bjarne M, Forslund, Terje
Zdroj: Nephrology Dialysis Transplantation; January 2005, Vol. 20 Issue: 1 p71-82, 12p
Abstrakt: The antifibrotic substance pirfenidone and the angiotensin II type I receptor antagonist candesartan cilexetil, given alone and in combination, were tested in rats with chronic anti-glomerular basement membrane glomerulonephritis (anti-GBM GN).
Databáze: Supplemental Index