Underlying Viral Etiology in Behcet's Disease: A Systematic Review

Autor: Ayodele, Victoria A.O., Akinsooto, Ayomide, Tchani, Raphaela, Bambekova, Pavela, Osswald, Sandra
Zdroj: Journal of the National Medical Association; August 2024, Vol. 116 Issue: 4 p428-428, 1p
Abstrakt: Bechet's disease is a rare auto-inflammatory systemic vasculitis characterized by recurrent oral and genital ulcerations, chronic uveitis, and vasculitis affecting arteries and veins of all sizes. Left untreated, it can lead to more severe complications such as stroke and blindness. Behcet's disease primarily affects individuals who are in their 20s to 40s, however the cause of the condition is still unknown. Additionally, there is a higher prevalence in Middle Eastern, Asian, and Mediterranean patients, suggesting a possible association with genetic predisposition and environmental influences. Other studies have indicated viral infection may play a role in the pathogenesis of Behcet's disease.
Databáze: Supplemental Index