Asymmetric Synthesis of 3-Substituted Isoindolinones:  Application to the Total Synthesis of (+)-Lennoxamine

Autor:	Comins, D. L., Schilling, S., Zhang, Y.
Zdroj:	Organic Letters; January 2005, Vol. 7 Issue: 1 p95-98, 4p
Abstrakt:	An anionic chiral auxiliary mediated asymmetric alkylation of carbamate 2 provides 3-substituted isoindolinones 4 in high ee. This methodology was used in the first asymmetric synthesis of (+)-lennoxamine.
Databáze:	Supplemental Index
Externí odkaz:	Zobrazit plný text záznamu