| Autor: |
Manisha, Manisha, Kumari, Sangeeta, Sharma, Deepak, Negi, Lalit, Joshi, Raj K. |
| Zdroj: |
The Journal of Organic Chemistry; September 2024, Vol. 89 Issue: 17 p11983-11993, 11p |
| Abstrakt: |
Sustainable and highly economical iron-catalyzed chemoselective reduction of C═C of α,β-unsaturated ketones has been established under mild reaction protocols. Water is used as a green and abundant surrogate of hydrogen and is scarcely used in organic synthetic transformations as a source of hydrogen. The developed protocol offers a broad spectrum for chemoselective transfer hydrogenation of α,β-unsaturated ketones. Moreover, the method was found to be highly effective for aryl and ferrocenyl α,β-unsaturated ketones consisting of one or two double bonds and with multiple functionalities. Moreover, the present method avoids prolonged reaction time, provides a wide range of substrates with excellent yield, and circumvents the tedious chromatographic workup. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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