PLAG1 overexpression in salivary gland duct-acinar units results in epithelial tumors with acinar-like features: Tumorization of luminal stem/progenitor cells may result in the developmen t of salivary gland tumors consisting of only luminal cells

Autor:	Ikeda, Yunosuke, Yasuhara, Rika, Tanaka, Junichi, Ida-Yonemochi, Hiroko, Akiyama, Haruhiko, Otsu, Keishi, Miyamoto, Ikuya, Harada, Hidemitsu, Yamada, Hiroyuki, Fukada, Toshiyuki, Irié, Tarou
Zdroj:	Journal of Oral Biosciences; 20240101, Issue: Preprints
Abstrakt:	Details about salivary gland tumor histogenesis remain unknown. Here, we established a newly generated murine salivary gland tumor model that could overexpress pleomorphic adenoma gene 1 (PLAG1) and attempted to clarify the events that occur during the early phase of salivary gland tumor histogenesis.
Databáze:	Supplemental Index
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