| Autor: |
Nonaka, Makoto, Kataoka, Daisuke, Yamamoto, Shigeru, Horichi, Naoya, Ohgiya, Yoshimitsu, Kushima, Miki, Kunimura, Toshiaki, Takaba, Toshihiro |
| Zdroj: |
Surgery Today; 20050101, Vol. 35 Issue: 1 p22-27, 6p |
| Abstrakt: |
Purpose To determine whether interlobar pleural invasion into the adjacent lobe (interlobar P3) should be assessed as T3 according to the tumor-node metastasis classification. Methods Surgically treated patients with primary lung cancer ( n = 322) were analyzed. Results Tumors with interlobar P3 had a significantly lower incidence of mass screening detection, a higher occurrence rate of squamous cell carcinoma, and a larger tumor diameter than tumors without interlobar P3. The lymph node metastatic rate did not differ between the patients with and without interlobar P3. The 5-year survival rate of patients with interlobar P3 was 63% and the rates of other patients were 56% with T1 disease, 57% with T2, 31% with T3, and 19% with T4. The survival rate for patients with interlobar P3 was higher than for those with T3 without interlobar P3 ( P < 0.05). The 5-year survival rate of the patients with interlobar P3 was lower in adenocarcinoma (39%) than in squamous cell carcinoma (69%, P < 0.01). The results were similar when the analysis was restricted to patients without lymph node metastasis. In adenocarcinoma, the survival rate for interlobar P3 was between the rates for T2 (53%) and T3 (13%) without interlobar P3, whereas in squamous cell carcinoma, the survival rate for interlobar P3 was between the rates for T1 (88%) and T2 (54%) without interlobar P3. Conclusion Tumors with interlobar P3 should be classified as T2 only in squamous cell carcinoma. |
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