| Autor: |
Serio, Pedro Adolpho de Menezes Pacheco, Saccaro, Daniela Marques, de Gouvêa, Ana Carolina Ribeiro Chaves, Encinas, Giselly, Maistro, Simone, Pereira, Gláucia Fernanda de Lima, Rocha, Vinícius Marques, de Souza, Larissa Dias, da Silva, Viviane Jennifer, Katayama, Maria Lucia Hirata, Folgueira, Maria Aparecida Azevedo Koike |
| Zdroj: |
Clinics; 20240101, Issue: Preprints |
| Abstrakt: |
•In breast cancer from young women:TP53 was affected in 75% of TN samples, in concomitance with at least one additional driver gene, mainly NF1, NOTCH1 or PTPN13.•In TN tumors carrying a wild type TP53, other drivers were TSG, like ATR and NF1.•PIK3CA and GATA3 were the main cancer driver genes in luminal samples, and candidate drivers were GRHL2 and SMURF2.•CACNA1E is a candidate cancer driver in both luminal and TN samples. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
