| Autor: |
Muscarella, Peter, Boros, Laszlo G., Fisher, William E., Rink, Cameron, Melvin, W.Scott |
| Zdroj: |
Journal of Surgical Research; October 1998, Vol. 79 Issue: 2 p154-157, 4p |
| Abstrakt: |
Background.Dehydroepiandrosterone (DHEA), an androgen precursor, inhibits the induction of pancreatic cancer in some animal models. Our laboratory has previously demonstrated that the sulfated form of DHEA (DHAS), when administered by intraperitoneal injection, inhibits the growth of pancreatic cancer xenografts in nude mice. In the present study, we hypothesize that DHEA-mediated pancreatic cancer growth inhibition is associated with alterations in plasma sex hormone concentrations. |
| Databáze: |
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