Role of Exercise Hemodynamics in the Prediction of Pulmonary Arterial Hypertension in BMPR2Mutation Carriers

Autor: Gerges, Christian, Beurnier, Antoine, Jaïs, Xavier, Hervé, Philippe, Lau, Edmund M.T., Girerd, Barbara, Günther, Sven, Bouchachi, Amir, Jevnikar, Mitja, Boucly, Athénaïs, Bogaard, Harm Jan, Simonneau, Gérald, Sitbon, Olivier, Savale, Laurent, Chemla, Denis, Humbert, Marc, Montani, David
Zdroj: Chest; November 2024, Vol. 166 Issue: 5 p1173-1183, 11p
Abstrakt: Exercise hemodynamics are recommended for early detection of pulmonary arterial hypertension (PAH) and have been suggested to be predictive of future development of PAH in high-risk populations such as BMPR2mutation carriers. However, the optimal exercise hemodynamic screening parameter remains to be determined. Recent data suggest that pulmonary vascular distensibility (α) may serve as a useful parameter for early detection of PAH.
Databáze: Supplemental Index