| Autor: |
Riley, Leanne M., Marshall, Olivia, Harkiss, Alexander H., Senn, Hans M., Sutherland, Andrew |
| Zdroj: |
Organic Letters; 20240101, Issue: Preprints |
| Abstrakt: |
Unnatural α-amino acids with charge transfer-based poly aromatic side chains have been designed as conformationally sensitive fluorophores. These were prepared using a hetero-Diels–Alder reaction and a Knoevenagel–Stobbe process to generate a biaryl pyridyl unit, followed by iron-catalyzed bromination and a Suzuki–Miyaura cross-coupling reaction to complete the triaryl system. A photophysical study led to the discovery of a p-methoxy analogue which exhibited viscosity-sensitive fluorescence in which emission could be controlled between twisted and planar conformations. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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