| Autor: |
Amato, J. S., Chung, J. Y. L., Cvetovich, R. J., Reamer, R. A., Zhao, D., Zhou, G., Gong, X. |
| Zdroj: |
Organic Process Research & Development; November 2004, Vol. 8 Issue: 6 p939-941, 3p |
| Abstrakt: |
Efficient trapping of dimethylamine was the key to success in the transamination of 1,1-dimethyl-4-oxopiperidinium iodide with tert-butylamine to afford 1-tert-butylpiperidin-4-one in high yield. The use of sodium acrylate was found to provide an elegant way to both trap dimethylamine and provide a convenient method to allow purification in the subsequent extraction. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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