Fasting and postprandial plasma metabolite responses to a 12-week dietary intervention in tissue-specific insulin resistance: a secondary analysis of the PERSON randomized trial

Autor: Gijbels, Anouk, Jardon, Kelly M., Trouwborst, Inez, Manusama, Koen C.M., Goossens, Gijs H., Blaak, Ellen E., Feskens, Edith J.M., Afman, Lydia A.
Zdroj: The American Journal of Clinical Nutrition; 20240101, Issue: Preprints
Abstrakt: We previously showed that dietary intervention effects on cardiometabolic health were driven by tissue-specific insulin resistance (IR) phenotype: individuals with predominant muscle IR (MIR) benefitted more from a low-fat, high-protein, high-fiber diet (LFHP), while individuals with predominant liver IR (LIR) benefitted more from a diet rich in mono-unsaturated fat (HMUFA).
Databáze: Supplemental Index