Synthesis of N3,5‘-Cyclo-4-(β-d-ribofuranosyl)-vic-triazolo[4,5-b]pyridin-5-one, a Novel Compound with Anti-Hepatitis C Virus Activity

Autor: Wang, P., Hollecker, L., Pankiewicz, K. W., Patterson, S. E., Whitaker, T., McBrayer, T. R., Tharnish, P. M., Sidwell, R. W., Stuyver, L. J., Otto, M. J., Schinazi, R. F., Watanabe, K. A.
Zdroj: Journal of Medicinal Chemistry; November 2004, Vol. 47 Issue: 24 p6100-6103, 4p
Abstrakt: A novel anti-hepatitis C virus (HCV) agent, N3,5‘-cyclo-4-(β-d-ribofuranosyl)-vic-triazolo[4,5-b]pyridinin-5-one, was identified, and the structure was confirmed by chemical synthesis from 2-hydroxy-5-nitropyridine.
Databáze: Supplemental Index